MIR4325

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR4325 RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated MIR4325 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher MIR4325 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4325 expression acts as an unfavorable survival marker.

SKCM, KIRC, and UCS are the cancer types where MIR4325 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMDFSTertileIII,IV0.0580.648.00118view →
KIRCDFSTertileIV0.2160.623.03518view →
UCSOSTertileAll0.1850.686.03418view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MIR4325–SKCM (DFS)

Kaplan–Meier survival curve for MIR4325 RNA-high vs -low samples in SKCM.

Open the SKCM breakdown →

Exploration