MIR4314

Across TCGA patient cohorts, MIR4314 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,587 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4314-associated GO terms across cancer lineages are Regulation of keratinocyte proliferation, Obsolete histone modification, and Peptidyl-lysine modification. Each is linked with MIR4314 in more than 6 cancer types. Because this analysis shows association rather than direction, both MIR4314-to-partner and partner-to-MIR4314 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of keratinocyte proliferation grouped by MIR4314-low versus MIR4314-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4314→partner) and Y-score (partner→MIR4314) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of keratinocyte proliferation →	+0.067	+0.402	<.001	<.001	3	7
STAD	Obsolete histone modification →	+0.074	+0.152	<.001	<.001	3	7
STAD	Peptidyl-lysine modification →	+0.072	+0.158	<.001	<.001	3	7
STAD	Regulation of signal transduction by p53 class mediator →	+0.077	+0.151	<.001	<.001	3	7
STAD	Positive regulation of signal transduction by p53 class mediator →	+0.071	+0.171	<.001	<.001	3	7
STAD	Regulation of intrinsic apoptotic signaling pathway by p53 class mediator →	+0.082	+0.211	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,587 associations by consensus.

Regulation of keratinocyte proliferation by MIR4314 expression — ESCA

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