MIR4312

Across TCGA pan-cancer cohorts, MIR4312 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MIR4312’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR4312 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4312 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

KIRC, LIHC, and HNSC are the cancer types where MIR4312 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4312 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.336	<.001	6	view →
LIHC	All	All	+0.235	.001	4	view →
HNSC	All	III,IV	+0.196	.012	4	view →
STAD	Male	II,III,IV	+0.728	.008	3	view →
PRAD	All	All	+0.354	.031	2	view →
CHOL	All	All	+0.946	.018	1	view →
LUSC	Female	III,IV	+0.945	.002	1	view →
BLCA	All	III,IV	+0.697	.033	1	view →
KIRP	All	All	−0.266	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

MIR4312–KIRC

Open the KIRC breakdown →