MIR4300HG

Across TCGA pan-cancer cohorts, MIR4300HG RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR4300HG’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4300HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4300HG is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BRCA, LUSC, and HNSC are the cancer types where MIR4300HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4300HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.124	<.001	6	view →
LUSC	All	All	+0.096	.002	4	view →
HNSC	Male	All	+0.025	.009	4	view →
THCA	Male	IV	−0.043	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR4300HG–BRCA

Open the BRCA breakdown →