MIR4289

Across TCGA patient cohorts, MIR4289 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,159 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4289-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Endocrine system development, and Regulation of Ras protein signal transduction. Each is linked with MIR4289 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR4289-to-partner and partner-to-MIR4289 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by MIR4289-low versus MIR4289-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4289→partner) and Y-score (partner→MIR4289) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of protein-containing complex assembly →	+0.123	+0.082	<.001	.004	3	3
STAD	Endocrine system development →	+0.067	+0.061	<.001	.003	3	3
STAD	Regulation of Ras protein signal transduction →	+0.106	+0.098	<.001	.002	3	3
STAD	Protein insertion into membrane →	+0.159	+0.073	<.001	<.001	3	3
STAD	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest →	+0.128	+0.066	<.001	.001	3	3
STAD	Establishment of protein localization to membrane →	+0.154	+0.063	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,159 associations by consensus.

Negative regulation of protein-containing complex assembly by MIR4289 expression — STAD

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