MIR4282

Across TCGA pan-cancer cohorts, MIR4282 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated MIR4282 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR4282 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4282 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

UVM, SARC, and LAML are the cancer types where MIR4282 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.220	0.917	<.001	54	view →
SARC	OS	Tertile	All	0.108	0.839	<.001	36	view →
LAML	DFS	Median	All	0.732	0.417	.002	24	view →
LUAD	DFS	Tertile	II,III,IV	0.229	0.725	<.001	18	view →
UCEC	OS	Tertile	All	0.138	0.679	.045	18	view →
PCPG	DFS	Tertile	All	0.532	0.924	<.001	18	view →
LUSC	OS	Tertile	All	0.160	0.401	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MIR4282–UVM (OS)

Open the UVM breakdown →