Q-omics provides the consensus-scored MIR4280 profile across patient tissues and cancer cell-line models. MIR4280 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in COAD. Additionally, MIR4280 RNA expression shows 5,455 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight COAD, and STAD as cancer lineages where MIR4280 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR4280 survival associations across molecular data types. MIR4280 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR4280 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	COAD (45)	view →

This table ranks reproducible MIR4280 RNA expression–survival associations across cancer types. High MIR4280 expression shows unfavorable associations in COAD, KIRC, LGG, BRCA and BLCA, but favorable associations in ESCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify COAD as the clearest survival context for MIR4280 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	IV	0.089	0.649	.005	45	view →
ESCA	DFS	Tertile	II,III,IV	0.816	0.285	.016	36	view →
KIRC	DFS	Tertile	IV	0.212	0.634	.001	36	view →
LGG	OS	Tertile	All	0.183	0.834	<.001	21	view →
BRCA	OS	Tertile	All	0.886	0.924	.023	12	view →
BLCA	DFS	Tertile	III,IV	0.166	0.572	.046	9	view →

Pink = unfavorable, green = favorable. all 7 lineages →

MIR4280-COAD (OS)

Kaplan–Meier survival curve for MIR4280 RNA expression in COAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR4280 in patient tissues and cancer cell lines. In patient samples, MIR4280 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,455	STAD (5141)	view →
RNA	4,957	COAD (1487)	view →