MIR4270

Across TCGA patient cohorts, MIR4270 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,964 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4270-associated GO terms across cancer lineages are Negative regulation of autophagosome maturation, Negative regulation of telomere maintenance via telomere lengthening, and Regulation of actin nucleation. Each is linked with MIR4270 in more than 3 cancer types. Because this analysis shows association rather than direction, both MIR4270-to-partner and partner-to-MIR4270 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagosome maturation grouped by MIR4270-low versus MIR4270-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4270→partner) and Y-score (partner→MIR4270) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of autophagosome maturation →	+0.070	+0.104	<.001	<.001	3	4
STAD	Negative regulation of telomere maintenance via telomere lengthening →	+0.098	+0.165	<.001	<.001	3	4
STAD	Regulation of actin nucleation →	+0.106	+0.173	<.001	<.001	3	4
STAD	Obsolete ncRNA catabolic process →	+0.122	+0.220	<.001	<.001	3	4
STAD	Apical junction assembly →	+0.103	+0.134	<.001	<.001	3	4
STAD	Obsolete regulation of transcription from RNA polymerase II promoter in response to stress →	+0.136	+0.170	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,964 associations by consensus.

Negative regulation of autophagosome maturation by MIR4270 expression — STAD

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