Across TCGA patient cohorts, MIR425 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,707 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MIR425-associated proteins across cancer lineages are TFE3_S548, EPS15_S851, and CDC42BPA_S940. Each is linked with MIR425 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR425-to-partner and partner-to-MIR425 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR425→partner) and Y-score (partner→MIR425) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TFE3_S548 →	-0.325	-0.709	<.001	<.001	3	3
HNSC	EPS15_S851 →	-0.443	-0.890	.003	<.001	3	3
OV	CDC42BPA_S940 →	+0.576	+1.228	.002	.002	3	2
OV	ADNP →	+0.244	+0.562	.002	.002	3	2
OV	CYBA →	-0.424	-0.552	.005	.004	3	2
OV	FGA →	-0.635	-0.457	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,707 associations by consensus.

Exploration

MIR425 survival (RNA) · tumor vs normal (RNA) · all MIR425 data types