Across TCGA pan-cancer cohorts, MIR422A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated MIR422A data layer compared with 9 for mass-spec protein.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MIR422A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR422A expression acts as an unfavorable survival marker.
BLCA are the cancer types where MIR422A Mutation most reproducibly stratifies survival.