Across TCGA patient cohorts, MIR422A mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR422A-associated genes across cancer lineages are ATP2B2-IT1, IGKV2OR2-7D, and NUDT4P2. Each is linked with MIR422A in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR422A-to-partner and partner-to-MIR422A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR422A→partner) and Y-score (partner→MIR422A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP2B2-IT1 →	+0.106	+5.582	<.001	.002	3	2
UCEC	IGKV2OR2-7D →	+0.269	+4.771	<.001	.006	3	1
UCEC	NUDT4P2 →	+0.089	+4.484	<.001	.009	3	1
UCEC	BNIP3P4 →	+0.119	+4.484	<.001	.009	3	1
UCEC	MIR3116-1 →	+0.747	+4.871	<.001	.002	3	1
UCEC	RPL23AP4 →	+0.240	+5.302	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

MIR422A survival (RNA) · tumor vs normal (RNA) · all MIR422A data types