Across TCGA pan-cancer cohorts, MIR3926-1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR3926-1’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR3926-1 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR3926-1 is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.
BRCA, LUSC, and BLCA are the cancer types where MIR3926-1 tumor–normal differential expression is most reproducible.