Across TCGA pan-cancer cohorts, MIR3908 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR3908’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where MIR3908 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR3908 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.
THCA and BRCA are the cancer types where MIR3908 tumor–normal differential expression is most reproducible.