Across TCGA pan-cancer cohorts, MIR3907 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR3907’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR3907 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR3907 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.
BRCA, LUAD, and KICH are the cancer types where MIR3907 tumor–normal differential expression is most reproducible.