MIR378J

Across TCGA pan-cancer cohorts, MIR378J RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated MIR378J data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR378J RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR378J expression acts as an unfavorable survival marker, although some lineages such as LUAD and BLCA show a favorable association.

KIRC, LUAD, and BLCA are the cancer types where MIR378J RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.464	0.705	<.001	76	view →
LUAD	OS	Median	II,III,IV	0.662	0.401	<.001	65	view →
BLCA	DFS	Quartile	All	0.439	0.207	.005	64	view →
READ	OS	Tertile	II,III,IV	1.000	0.848	<.001	55	view →
LUSC	OS	Tertile	II,III,IV	0.180	0.692	<.001	46	view →
CESC	DFS	Tertile	All	0.768	0.896	.001	36	view →
UVM	DFS	Tertile	III,IV	0.095	1.000	.004	33	view →
STAD	DFS	Median	II,III,IV	0.471	0.599	.008	25	view →
LIHC	DFS	Tertile	II,III,IV	0.240	0.436	.009	25	view →
UCS	DFS	Tertile	IV	0.936	0.488	.024	24	view →
LGG	DFS	Median	All	0.679	0.793	.001	24	view →
SKCM	DFS	Tertile	All	0.778	0.652	.009	23	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

MIR378J–KIRC (DFS)

Open the KIRC breakdown →