MIR378E

Across TCGA pan-cancer cohorts, MIR378E RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR378E data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MIR378E RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR378E expression acts as an unfavorable survival marker.

MESO, DLBC, and READ are the cancer types where MIR378E RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.201	0.576	.010	54	view →
DLBC	DFS	Tertile	III,IV	0.074	0.984	.003	48	view →
READ	DFS	Tertile	All	0.446	0.851	.005	27	view →
STAD	DFS	Tertile	All	0.520	0.682	.005	24	view →
SKCM	DFS	Tertile	All	0.255	0.642	.008	12	view →
GBM	DFS	Tertile	All	0.081	0.296	.029	9	view →
THYM	DFS	Tertile	II,III,IV	0.091	0.842	.001	9	view →
LIHC	DFS	Tertile	II,III,IV	0.100	0.463	.048	9	view →
SARC	DFS	Tertile	All	0.101	0.632	.011	9	view →
KIRP	OS	Tertile	All	0.335	0.728	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR378E–MESO (OS)

Open the MESO breakdown →