MIR378D2HG

Across TCGA pan-cancer cohorts, MIR378D2HG RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of MIR378D2HG’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR378D2HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR378D2HG is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

LUSC, COAD, and KIRC are the cancer types where MIR378D2HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR378D2HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	All	+0.341	<.001	8	view →
COAD	Male	All	+0.223	<.001	7	view →
KIRC	Male	III,IV	−0.151	<.001	7	view →
KICH	Female	II,III,IV	+0.825	<.001	6	view →
LUAD	All	All	+0.170	<.001	5	view →
STAD	All	All	+0.122	.005	5	view →
BRCA	All	II,III,IV	+0.159	.001	4	view →
LIHC	All	All	+0.038	.001	4	view →
HNSC	Male	All	+0.102	.016	3	view →
CHOL	All	All	+0.335	.004	2	view →
UCEC	All	All	+0.299	.001	2	view →
KIRP	All	IV	−0.142	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

MIR378D2HG–LUSC

Open the LUSC breakdown →