MIR378C

Across TCGA patient cohorts, MIR378C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,401 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR378C-associated GO terms across cancer lineages are Regulation of response to endoplasmic reticulum stress, Regulation of DNA damage checkpoint, and Negative regulation of double-strand break repair via homologous recombination. Each is linked with MIR378C in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR378C-to-partner and partner-to-MIR378C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of response to endoplasmic reticulum stress grouped by MIR378C-low versus MIR378C-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR378C→partner) and Y-score (partner→MIR378C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of response to endoplasmic reticulum stress →	+0.234	+0.064	<.001	<.001	3	4
STAD	Regulation of DNA damage checkpoint →	+0.225	+0.066	<.001	<.001	3	4
STAD	Negative regulation of double-strand break repair via homologous recombination →	+0.180	+0.123	<.001	<.001	3	4
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.198	+0.060	<.001	<.001	3	4
STAD	Regulation of DNA biosynthetic process →	+0.215	+0.066	<.001	<.001	3	4
STAD	Positive regulation of DNA biosynthetic process →	+0.216	+0.062	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,401 associations by consensus.

Regulation of response to endoplasmic reticulum stress by MIR378C expression — STAD

Explore this box plot interactively →