MIR378C

Across TCGA patient cohorts, MIR378C mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR378C-associated genes across cancer lineages are MIR4698, MIR3692, and RNA5SP197. Each is linked with MIR378C in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR378C-to-partner and partner-to-MIR378C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4698 grouped by MIR378C-low versus MIR378C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR378C→partner) and Y-score (partner→MIR378C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4698 →	+0.673	+5.031	.001	.009	3	1
UCEC	MIR3692 →	+0.717	+6.877	<.001	<.001	3	1
UCEC	RNA5SP197 →	+1.387	+5.242	<.001	.007	3	1
UCEC	RNY3P11 →	+0.868	+5.484	<.001	.005	3	1
UCEC	RNY1P1 →	+0.648	+6.335	<.001	.001	3	1
UCEC	RNA5SP72 →	+0.794	+5.031	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MIR4698 by MIR378C expression — UCEC

Explore this box plot interactively →