Across TCGA pan-cancer cohorts, MIR374B Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated MIR374B data layer compared with 22 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR374B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR374B expression acts as an unfavorable survival marker.

COAD are the cancer types where MIR374B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.235	0.790	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: MIR374B tumor-vs-normal RNA expression · all MIR374B data types