Across TCGA pan-cancer cohorts, MIR3679 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR3679’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where MIR3679 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR3679 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
STAD, LUAD, and LUSC are the cancer types where MIR3679 tumor–normal differential expression is most reproducible.