MIR3648-2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR3648-2 RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated MIR3648-2 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher MIR3648-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR3648-2 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

LUSC, SKCM, and THYM are the cancer types where MIR3648-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSTertileAll0.1960.664<.00196view →
SKCMDFSTertileAll0.2250.740<.00163view →
THYMDFSTertileAll0.1230.871<.00136view →
SARCOSTertileAll0.0290.839<.00136view →
LAMLDFSMedianAll0.6720.485.01214view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MIR3648-2–LUSC (DFS)

Kaplan–Meier survival curve for MIR3648-2 RNA-high vs -low samples in LUSC.

Open the LUSC breakdown →

Exploration