Across TCGA pan-cancer cohorts, MIR3609 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR3609’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where MIR3609 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR3609 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
KICH, LIHC, and COAD are the cancer types where MIR3609 tumor–normal differential expression is most reproducible.