Across TCGA pan-cancer cohorts, MIR340 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR340’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR340 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR340 is over-expressed in tumor.
BRCA, LUAD, and LIHC are the cancer types where MIR340 tumor–normal differential expression is most reproducible.