MIR323A

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR323A Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MIR323A data layer compared with 4 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher MIR323A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR323A expression acts as an unfavorable survival marker.

SKCM, LUAD, and PRAD are the cancer types where MIR323A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMOSMedianAll0.3250.785<.00131view →
LUADOSMedianAll0.0900.812<.00124view →
PRADDFSMedianAll0.0850.774<.0016view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration