Across TCGA pan-cancer cohorts, MIR3197 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR3197’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where MIR3197 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR3197 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
KICH, COAD, and THCA are the cancer types where MIR3197 tumor–normal differential expression is most reproducible.