MIR3180-5

Across TCGA pan-cancer cohorts, MIR3180-5 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR3180-5 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher MIR3180-5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR3180-5 expression acts as an unfavorable survival marker.

LUSC, SKCM, and PAAD are the cancer types where MIR3180-5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	III,IV	0.010	0.754	<.001	54	view →
SKCM	DFS	Tertile	III,IV	0.166	0.608	<.001	42	view →
PAAD	OS	Tertile	II,III,IV	0.210	0.556	.007	36	view →
MESO	OS	Tertile	II,III,IV	0.241	0.575	.016	36	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
KIRC	OS	Tertile	All	0.453	0.635	.043	12	view →
BLCA	OS	Tertile	IV	0.388	0.608	.027	9	view →
GBM	DFS	Tertile	All	0.061	0.288	<.001	9	view →
LUAD	OS	Tertile	All	0.250	0.697	.046	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MIR3180-5–LUSC (DFS)

Open the LUSC breakdown →