MIR3161

Across TCGA patient cohorts, MIR3161 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,746 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR3161-associated GO terms across cancer lineages are Negative regulation of epidermal growth factor receptor signaling pathway, Response to endoplasmic reticulum stress, and Vesicle-mediated transport to the plasma membrane. Each is linked with MIR3161 in more than 20 cancer types. Because this analysis shows association rather than direction, both MIR3161-to-partner and partner-to-MIR3161 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of epidermal growth factor receptor signaling pathway grouped by MIR3161-low versus MIR3161-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR3161→partner) and Y-score (partner→MIR3161) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of epidermal growth factor receptor signaling pathway →	+0.058	+0.834	<.001	<.001	3	21
ESCA	Response to endoplasmic reticulum stress →	+0.072	+1.167	<.001	<.001	3	20
STAD	Vesicle-mediated transport to the plasma membrane →	+0.045	+0.681	<.001	<.001	3	19
ESCA	Vesicle localization →	+0.040	+0.802	.003	<.001	3	19
ESCA	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.055	+0.918	<.001	<.001	3	19
STAD	Endosomal transport →	+0.048	+0.695	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,746 associations by consensus.

Negative regulation of epidermal growth factor receptor signaling pathway by MIR3161 expression — ESCA

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