MIR3156-2

Across TCGA pan-cancer cohorts, MIR3156-2 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated MIR3156-2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR3156-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR3156-2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

HNSC, SKCM, and UVM are the cancer types where MIR3156-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.163	0.696	.007	72	view →
SKCM	DFS	Tertile	III,IV	0.899	0.487	.018	36	view →
UVM	OS	Tertile	II,III,IV	0.288	0.651	.016	27	view →
ESCA	DFS	Tertile	III,IV	1.000	0.280	.042	12	view →
STAD	OS	Tertile	IV	1.000	0.299	.047	6	view →
BRCA	DFS	Tertile	II,III,IV	0.975	0.937	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MIR3156-2–HNSC (DFS)

Open the HNSC breakdown →