Across TCGA pan-cancer cohorts, MIR3139 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR3139’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR3139 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR3139 is over-expressed in tumor.
KIRC and THCA are the cancer types where MIR3139 tumor–normal differential expression is most reproducible.