Across TCGA pan-cancer cohorts, MIR3129 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR3129’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where MIR3129 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR3129 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
STAD, LUSC, and THCA are the cancer types where MIR3129 tumor–normal differential expression is most reproducible.