Across TCGA pan-cancer cohorts, MIR3117 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MIR3117’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MIR3117 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR3117 is over-expressed in tumor, although a few such as KIRP and LUAD show the opposite, repressed pattern.
KIRP, LUAD, and KIRC are the cancer types where MIR3117 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR3117 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.