MIR3116-1

Across TCGA pan-cancer cohorts, MIR3116-1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MIR3116-1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher MIR3116-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR3116-1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and THCA show a favorable association.

READ, TGCT, and ACC are the cancer types where MIR3116-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	III,IV	0.581	0.924	<.001	117	view →
TGCT	OS	Tertile	III,IV	0.003	1.000	<.001	54	view →
ACC	DFS	Tertile	All	0.057	0.667	<.001	45	view →
HNSC	OS	Tertile	IV	0.149	0.667	<.001	36	view →
BRCA	OS	Tertile	II,III,IV	0.949	0.903	.026	18	view →
SARC	OS	Tertile	All	0.109	0.827	<.001	18	view →
OV	DFS	Median	IV	0.346	0.544	.026	14	view →
THCA	DFS	Tertile	All	0.987	0.926	.022	9	view →
COAD	DFS	Tertile	II,III,IV	0.173	0.478	.014	9	view →
ESCA	OS	Median	All	0.602	0.742	.030	5	view →
LUSC	OS	Quartile	III,IV	0.220	0.462	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MIR3116-1–READ (OS)

Open the READ breakdown →