MIR3115

Across TCGA pan-cancer cohorts, MIR3115 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR3115 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MIR3115 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR3115 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

MESO, THCA, and KIRC are the cancer types where MIR3115 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	II,III,IV	0.046	0.383	<.001	99	view →
THCA	DFS	Tertile	All	0.432	0.819	.017	30	view →
KIRC	OS	Tertile	II,III,IV	0.319	0.545	.021	18	view →
OV	DFS	Tertile	IV	0.229	0.481	.015	18	view →
TGCT	OS	Tertile	All	0.542	0.968	.001	18	view →
LGG	DFS	Tertile	All	0.630	0.833	.007	12	view →
UCEC	DFS	Tertile	All	0.227	0.669	.016	12	view →
LAML	DFS	Tertile	All	0.586	0.278	.025	8	view →
STAD	OS	Quartile	IV	0.111	0.466	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MIR3115–MESO (DFS)

Open the MESO breakdown →