Across TCGA pan-cancer cohorts, MIR2276 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR2276’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where MIR2276 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR2276 is over-expressed in tumor, although a few such as LUSC and KIRC show the opposite, repressed pattern.
STAD, LUSC, and KIRC are the cancer types where MIR2276 tumor–normal differential expression is most reproducible.