MIR223HG

Across TCGA pan-cancer cohorts, MIR223HG RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of MIR223HG’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR223HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR223HG is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

KIRC, LUAD, and LUSC are the cancer types where MIR223HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR223HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.731	<.001	11	view →
LUAD	Male	III,IV	−1.984	<.001	9	view →
LUSC	Female	All	−2.201	<.001	8	view →
KICH	All	II,III,IV	−0.773	<.001	7	view →
UCEC	All	All	−0.773	<.001	6	view →
BRCA	All	III,IV	−0.724	<.001	6	view →
BLCA	Male	All	−0.633	.003	6	view →
THCA	All	IV	+0.827	<.001	5	view →
HNSC	All	IV	−0.441	.005	4	view →
PAAD	Male	All	−1.620	.013	2	view →
LIHC	Male	All	−0.246	.005	2	view →
CHOL	All	All	+0.575	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

MIR223HG–KIRC

Open the KIRC breakdown →