Across TCGA patient cohorts, MIR221 RNA expression is significantly associated with the RNA expression of many other genes, with 15,908 significant associations in total. THYM shows the largest number of these associations.

The most reproducible MIR221-associated genes across cancer lineages are MIR222HG, SNORD63B, and NEAT1. Each is linked with MIR221 in more than 31 cancer types. Because this analysis shows association rather than direction, both MIR221-to-partner and partner-to-MIR221 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR221→partner) and Y-score (partner→MIR221) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	MIR222HG →	+1.582	+1.988	<.001	<.001	3	32
DLBC	SNORD63B →	+1.683	+1.152	<.001	<.001	3	30
UVM	NEAT1 →	+1.437	+0.782	<.001	<.001	3	28
UVM	CCNL1 →	+1.233	+0.853	<.001	<.001	3	27
DLBC	LENG8 →	+1.383	+1.066	<.001	<.001	3	27
DLBC	MIRLET7D →	+1.641	+1.908	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,908 associations by consensus.

Exploration

MIR221 survival (RNA) · tumor vs normal (RNA) · all MIR221 data types