Q-omics provides the consensus-scored MIR216B profile across patient tissues and cancer cell-line models. MIR216B expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in BRCA. Additionally, MIR216B RNA expression shows 7,865 significant protein co-abundance associations, with the highest sampling consensus in PDAC. Together, these results highlight BRCA, and PDAC as cancer lineages where MIR216B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR216B survival associations across molecular data types. MIR216B RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR216B data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	BRCA (90)	view →

This table ranks reproducible MIR216B RNA expression–survival associations across cancer types. High MIR216B expression shows unfavorable associations in BRCA, BLCA, LUSC, LGG and UCEC, but favorable associations in HNSC. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for MIR216B RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	II,III,IV	0.001	0.958	<.001	90	view →
BLCA	OS	Tertile	All	0.074	0.720	<.001	72	view →
LUSC	OS	Tertile	II,III,IV	0.170	0.631	.003	45	view →
LGG	DFS	Tertile	All	0.236	0.739	.001	36	view →
HNSC	DFS	Tertile	All	1.000	0.594	.016	27	view →
UCEC	DFS	Tertile	All	0.123	0.648	.008	18	view →

Pink = unfavorable, green = favorable. all 6 lineages →

MIR216B-BRCA (OS)

Kaplan–Meier survival curve for MIR216B RNA expression in BRCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR216B in patient tissues and cancer cell lines. In patient samples, MIR216B shows the broadest associations at the RNA and protein expression levels, with PDAC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	7,865	PDAC (5551)	view →
RNA	7,411	UCEC (4813)	view →
▼Mutation
RNA	7	UCEC (7)	view →