Across TCGA pan-cancer cohorts, MIR216A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MIR216A data layer compared with 6 for mass-spec protein.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR216A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR216A expression acts as an unfavorable survival marker.
COAD and SKCM are the cancer types where MIR216A Mutation most reproducibly stratifies survival.