MIR2116

Across TCGA pan-cancer cohorts, MIR2116 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MIR2116 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MIR2116 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR2116 expression acts as an unfavorable survival marker, although some lineages such as UCS and UCEC show a favorable association.

UCS, LUAD, and LGG are the cancer types where MIR2116 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	IV	0.952	0.367	.001	42	view →
LUAD	OS	Quartile	All	0.202	0.458	.005	42	view →
LGG	DFS	Quartile	All	0.624	0.772	<.001	36	view →
LIHC	DFS	Tertile	All	0.299	0.480	.001	36	view →
SKCM	DFS	Quartile	All	0.485	0.708	<.001	35	view →
UCEC	OS	Tertile	IV	0.937	0.615	.019	30	view →
ACC	DFS	Quartile	All	0.447	0.718	.003	23	view →
TGCT	DFS	Quartile	II,III,IV	0.587	1.000	.008	18	view →
LUSC	OS	Tertile	All	0.819	0.688	.006	14	view →
THYM	DFS	Median	III,IV	1.000	0.441	.004	12	view →
LAML	DFS	Median	All	0.441	0.700	.016	12	view →
THCA	OS	Quartile	All	0.984	0.996	.021	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MIR2116–UCS (DFS)

Open the UCS breakdown →