MIR2115

Across TCGA pan-cancer cohorts, MIR2115 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated MIR2115 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher MIR2115 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR2115 expression acts as an unfavorable survival marker.

SKCM, TGCT, and COAD are the cancer types where MIR2115 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.590	0.876	<.001	120	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	36	view →
COAD	OS	Tertile	III,IV	0.142	0.792	<.001	36	view →
THCA	OS	Tertile	IV	0.095	0.966	<.001	36	view →
LUSC	OS	Tertile	II,III,IV	0.210	0.634	.005	36	view →
BLCA	DFS	Tertile	All	0.400	0.630	.037	18	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →
KIRP	OS	Tertile	All	0.545	0.907	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

MIR2115–SKCM (OS)

Open the SKCM breakdown →