MIR2114

Across TCGA pan-cancer cohorts, MIR2114 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MIR2114 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MIR2114 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR2114 expression acts as an unfavorable survival marker, although some lineages such as ACC show a favorable association.

MESO, ESCA, and KIRC are the cancer types where MIR2114 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.162	0.555	<.001	90	view →
ESCA	OS	Tertile	III,IV	0.108	0.574	<.001	63	view →
KIRC	OS	Tertile	All	0.367	0.636	.006	54	view →
STAD	DFS	Tertile	All	0.268	0.722	<.001	45	view →
LUAD	OS	Tertile	All	0.156	0.788	<.001	36	view →
READ	OS	Tertile	II,III,IV	0.542	0.919	.005	36	view →
BRCA	DFS	Tertile	II,III,IV	0.855	0.944	.005	24	view →
LAML	DFS	Tertile	All	0.241	0.594	.035	18	view →
UCEC	OS	Tertile	All	0.269	0.700	.004	12	view →
LIHC	DFS	Tertile	All	0.043	0.527	<.001	9	view →
ACC	DFS	Tertile	II,III,IV	1.000	0.383	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MIR2114–MESO (OS)

Open the MESO breakdown →