MIR2052HG

Across TCGA pan-cancer cohorts, MIR2052HG RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of MIR2052HG’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR2052HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR2052HG is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, LUSC, and BLCA are the cancer types where MIR2052HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR2052HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.427	<.001	12	view →
LUSC	Female	All	+0.732	<.001	7	view →
BLCA	All	All	+0.405	.003	7	view →
STAD	All	II,III,IV	+0.259	<.001	6	view →
LIHC	All	All	+0.179	.002	6	view →
LUAD	All	All	+0.211	<.001	4	view →
KICH	Male	III,IV	−0.060	.006	3	view →
PRAD	All	All	+0.393	.004	2	view →
UCEC	All	All	+0.075	.036	2	view →
COAD	All	All	+0.075	.024	2	view →
CHOL	All	All	+0.093	.035	1	view →
THCA	All	All	−0.031	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

MIR2052HG–HNSC

Open the HNSC breakdown →