MIR200CHG

Across TCGA pan-cancer cohorts, MIR200CHG RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MIR200CHG’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR200CHG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR200CHG is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and BLCA are the cancer types where MIR200CHG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR200CHG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−2.986	<.001	12	view →
KIRP	Female	All	−2.430	<.001	9	view →
BLCA	All	All	+1.882	.007	7	view →
BRCA	All	All	+1.089	<.001	6	view →
COAD	All	II,III,IV	+0.642	<.001	6	view →
THCA	Female	All	+0.685	<.001	4	view →
LUAD	All	All	−0.355	.016	4	view →
STAD	All	All	+1.243	.002	3	view →
UCEC	All	All	+2.289	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

MIR200CHG–KIRC

Open the KIRC breakdown →