MIR1976

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR1976 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated MIR1976 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MIR1976 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR1976 expression acts as an unfavorable survival marker.

BRCA, OV, and ESCA are the cancer types where MIR1976 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSTertileIII,IV0.1800.906<.00136view →
OVDFSTertileAll0.2680.543.00636view →
ESCAOSTertileII,III,IV0.4410.701.01927view →
BLCADFSTertileIV0.0990.480<.00118view →
LUSCDFSTertileIII,IV0.1240.632.01618view →
UCECOSTertileIV0.2310.592.03618view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MIR1976–BRCA (OS)

Kaplan–Meier survival curve for MIR1976 RNA-high vs -low samples in BRCA.

Open the BRCA breakdown →

Exploration