MIR1972-2

Across TCGA patient cohorts, MIR1972-2 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR1972-2-associated genes across cancer lineages are PRAMEF32P, AQP7P3, and MIR1343. Each is linked with MIR1972-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR1972-2-to-partner and partner-to-MIR1972-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF32P grouped by MIR1972-2-low versus MIR1972-2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR1972-2→partner) and Y-score (partner→MIR1972-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRAMEF32P →	+0.044	+7.930	<.001	.008	3	2
UCEC	AQP7P3 →	+0.030	+4.582	.002	.005	3	2
SKCM	MIR1343 →	+0.325	+5.469	<.001	.002	3	1
SKCM	RNU7-174P →	+0.377	+4.680	<.001	.007	3	1
SKCM	MTND4P7 →	+0.299	+5.254	<.001	.001	3	1
SKCM	GTF2IP11 →	+0.123	+4.680	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

PRAMEF32P by MIR1972-2 expression — LUAD

Explore this box plot interactively →