MIR1972-1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR1972-1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MIR1972-1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR1972-1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1972-1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, BRCA, and BLCA are the cancer types where MIR1972-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR1972-1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleIV+0.430.0127view →
BRCAFemaleAll+0.410.0036view →
BLCAAllAll+0.526.0075view →
THCAAllAll−0.267.0073view →
PAADFemaleAll+1.380.0012view →
LIHCAllAll+0.150.0111view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

MIR1972-1–KIRC

Tumor-vs-normal expression box plot for MIR1972-1 RNA in KIRC.

Open the KIRC breakdown →

Exploration