MIR194-1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR194-1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MIR194-1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MIR194-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR194-1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LAML show a favorable association.

THCA, KIRP, and OV are the cancer types where MIR194-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileAll0.9290.983.00245view →
KIRPOSTertileAll0.8680.946.01039view →
OVDFSTertileIV0.1770.487.00136view →
UCECDFSTertileIV1.0000.355.01636view →
SKCMOSTertileII,III,IV0.1750.391.01118view →
UVMOSTertileIII,IV0.2410.765.00218view →
LGGOSTertileAll0.7280.858.02112view →
LAMLDFSMedianAll0.5080.265.01710view →
COADOSTertileIV0.3710.680.0369view →
LUSCDFSQuartileIII,IV0.3290.592.0108view →
PRADOSTertileAll0.8220.902.0356view →
LUADOSQuartileAll0.7460.667.0491view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration