Across TCGA pan-cancer cohorts, MIR1915 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR1915’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MIR1915 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR1915 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
KIRP, THCA, and KICH are the cancer types where MIR1915 tumor–normal differential expression is most reproducible.