Across TCGA patient cohorts, MIR191 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,495 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR191-associated GO terms across cancer lineages are Negative regulation of mRNA processing, DNA integrity checkpoint signaling, and Negative regulation of RNA splicing. Each is linked with MIR191 in more than 6 cancer types. Because this analysis shows association rather than direction, both MIR191-to-partner and partner-to-MIR191 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR191→partner) and Y-score (partner→MIR191) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of mRNA processing →	+0.059	+0.147	<.001	<.001	3	6
KIRP	DNA integrity checkpoint signaling →	+0.034	+0.102	<.001	.001	3	6
ESCA	Negative regulation of RNA splicing →	+0.064	+0.142	<.001	.001	3	6
ESCA	Positive regulation of DNA recombination →	+0.046	+0.123	<.001	<.001	3	6
LUSC	Regulation of RNA export from nucleus →	+0.047	+0.071	<.001	.003	3	5
ESCA	DNA modification →	+0.043	+0.124	.005	.007	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,495 associations by consensus.

Exploration

MIR191 survival (RNA) · tumor vs normal (RNA) · all MIR191 data types